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Rescue teams were searching for survivors in the cliffside and in the river, it said.
It was not immediately clear what caused the bus to go off the road. Images from the scene showed a steep crag overlooking the riverbed where searchers were scrambling over boulders.
The Syrian Observatory for Human Rights, a UK-based war monitor, said the children had been attending a Qur’an memorization institute, of which there are many in northwest Syria.
It was the latest tragedy to affect an area that has already been hit hard by Syria’s ongoing civil war and by a devastating 7.8 magnitude earthquake that hit Turkiye and northern Syria last year.
Most of most of the 5.1 million people living in opposition-held northwest Syria have been internally displaced, sometimes more than once, in the country’s civil war, now in its 14th year, and rely on aid to survive.
AFP